Doctors & patients are saying about 'A-Fib.com'...


"A-Fib.com is a great web site for patients, that is unequaled by anything else out there."

Dr. Douglas L. Packer, MD, FHRS, Mayo Clinic, Rochester, MN

"Jill and I put you and your work in our prayers every night. What you do to help people through this [A-Fib] process is really incredible."

Jill and Steve Douglas, East Troy, WI 

“I really appreciate all the information on your website as it allows me to be a better informed patient and to know what questions to ask my EP. 

Faye Spencer, Boise, ID, April 2017

“I think your site has helped a lot of patients.”

Dr. Hugh G. Calkins, MD  Johns Hopkins,
Baltimore, MD


Doctors & patients are saying about 'Beat Your A-Fib'...


"If I had [your book] 10 years ago, it would have saved me 8 years of hell.”

Roy Salmon, Patient, A-Fib Free,
Adelaide, Australia

"This book is incredibly complete and easy-to-understand for anybody. I certainly recommend it for patients who want to know more about atrial fibrillation than what they will learn from doctors...."

Pierre Jaïs, M.D. Professor of Cardiology, Haut-Lévêque Hospital, Bordeaux, France

"Dear Steve, I saw a patient this morning with your book [in hand] and highlights throughout. She loves it and finds it very useful to help her in dealing with atrial fibrillation."

Dr. Wilber Su,
Cavanaugh Heart Center, 
Phoenix, AZ

"...masterful. You managed to combine an encyclopedic compilation of information with the simplicity of presentation that enhances the delivery of the information to the reader. This is not an easy thing to do, but you have been very, very successful at it."

Ira David Levin, heart patient, 
Rome, Italy

"Within the pages of Beat Your A-Fib, Dr. Steve Ryan, PhD, provides a comprehensive guide for persons seeking to find a cure for their Atrial Fibrillation."

Walter Kerwin, MD, Cedars-Sinai Medical Center, Los Angeles, CA


Adagio Medical

2018 AF Symposium: Innovative iCLAS Cyro Catheter by Adagio Medical

by Steve S. Ryan, PhD.

I knew it was something special by the incredibly high-powered, renowned presenters: two of the most important people in the treatment of Atrial Fibrillation―Dr. James Cox of the original Cox Maze operation and Prof. Michel Haissaguerre of the original PVI catheter ablation.

iCLAS Cryo ablation catheter hand graphic at A-Fib.com

iCLAS catheter (Continuous Lesion Ablation System) by Adagio Medical

One of the most fascinating presentations at the Product Theatre on Friday, January 12, was about the innovative, ultra-low temperature iCLAS catheter. Dr. Hugh Calkins of Johns Hopkins was the session moderator. The panel of presenters were:

James Cox of NW Feinberg Sch. of Medicine in Chicago, IL
Professor Michel Haissaguerre of the Bordeaux LIRYC group
Tom de Potter of the Cardiovascular Center in Aalst, Belgium
Lucas Boersma of AMC/U. of Amsterdam, The Netherlands
Alex Babkin, Chief Technical Officer of Adagio Medical

One Catheter. Unlimited Shapes.

Examples of the many different configurations of the iCLAS

The iCLAS catheter is a Cryo catheter that uses ultra-low temperatures and is unlike anything currently on the market. The catheter can be manipulated into many different configurations depending on the lesions which need to be made.

When I visited the Adagio booth, it was fascinating to see how easily the catheter could be designed into unlimited profiles.

Using its full length, the catheter can produce ultra low temperatures along its whole span (110mm). It has 20 electrodes which can also produce cryo-mapping of the atria.

For Flutter Ablations in the Caviotricuspid Isthmus in the right atrium, a shorter catheter is used with a continuous length of 54mm. It can also do Focal Tip Ablations. (The temperatures are so cold they use a heating balloon in the esophagus to prevent any damage.)

About Adagio Medical, Inc.: It’s a privately held medical device company founded in 2011 by Dr. James Cox and Mr. Olav Bergheim. It uses liquid nitrogen to produce ultra-low temperature lesions and developed Near Critical Nitrogen (NCN) technology which permits liquid nitrogen to be used in catheters inside the heart.

VIDEO Animation: iCLAS Catheter by Adagio Medical

Check out this excellent animation of the ultra-low temperature iCLAS catheter. With titles and music, illustrates examples of the creation of long and continuous lesions with full transmurality via endocardial approach with small size catheters (≤9Fr). (1:45) Produced by Adagio Medical, Inc.

YouTube video playback controls: When watching this video, you have several playback options. Settings (speed/quality) are located in the lower right portion of the frame, along with the option to enlarge video to full frame. 

Editor’s Comments:
Why is the iCLAS Cryo catheter special and innovative? The iCLAS catheter produces ablation lesions like current CryoBalloon catheters but at lower temperatures (colder). One would expect that such ultra-low Cryo lesions would be deeper, more transmural, and more lasting. In addition, the ability to produce unlimited shapes gives the iCLAS catheter a unique ability to position Cryo lesions in a variety of locations in the heart. It will make ablations much simpler and easier for EPs.
Historical! Attendees at this AF Symposium presentation were amazed and astounded by the possibilities of the iCLAS system. Endorsed by Dr. James Cox and Prof. Michel Haissaguerre, it was a historical breakthrough moment that few present will ever forget.
Next Great Breakthrough in Treating A-Fib! The iCLAS ultra-low temperature catheter with its unique ability to configure in unlimited shapes is the next great breakthrough in treating A-Fib! Barring any unforeseen problems with approval by the FDA, it will become the treatment of choice for ablating A-Fib/Flutter. (You heard it here first, folks!)

If you find any errors on this page, email us. Y Last updated: Wednesday, February 28, 2018

Back to 2018 AF Symposium Reports

Follow Us
facebook - A-Fib.comtwitter - A-Fib.comlinkedin  - A-Fib.compinterest  - A-Fib.comYouTube: A-Fib Can be Cured!  - A-Fib.com


A-Fib.com is a
501(c)(3) Nonprofit



Your support is needed. Every donation helps, even just $1.00.



A-Fib.com top rated by Healthline.com for fourth year 2014  2015  2016  2017

A-Fib.com Mission Statement
We Need You

Mug - Seek your cure - Beat Your A-Fib 200 pix wide at 300 resEncourage others
with A-Fib
click to order

Home | The A-Fib Coach | Help Support A-Fib.com | A-Fib News Archive | Tell Us What You think | Press Room | GuideStar Seal | HON certification | Disclosures | Terms of Use | Privacy Policy