2026 AF Symposium: Safety of Pulsed Field Ablation (PFA) vs Radiofrequency Ablation for A-Fib
The 2026 AF Symposium had two full sessions with several speakers on the safety of Pulsed Field Ablation (PFA) for treating Atrial Fibrillation, reflecting the increased scrutiny and challenges that have arisen with the rapid, widespread adoption of Pulsed Field Ablation.
Safety of PFA—Session 1: Complications Associated with Pulsed Field vs Radiofrequency Ablation for AF
Dr. Hugh Calkins (Johns Hopkins Hospital, Baltimore, MD) described how 28 years ago Pulmonary Vein Isolation/Ablation (PVI) with Radio Frequency (RF), i.e., thermal energy, became the cornerstone of treating A-Fib. The good news is that over time the complication rate for catheter ablation, i.e., Pulmonary Vein Isolation/Ablation, has decreased remarkedly down to less than 1% (from a high of 6%).
Pulsed Field Ablation (PFA) has a low complication rate and is recognized as a major safety improvement over RF ablation. It avoids much of the damage seen with RF (thermal energy) ablation. Furthermore, it doesn’t harm adjacent tissue.
But according to Dr. Calkins, “sadly we are still discovering new complications.” Continue reading about PFA complications in my report->






