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2026 AF Symposium: The ADVENT-LTO 4-Year Study of PFA vs. Thermal Ablations
Dr. Vivek Reddy
Considering a Catheter Ablation for your Atrial Fibrillation? To make an informed decision of type of catheter ablation, read about the findings from the ADVNT-LTO study that compared the newer Pulsed Field Ablation to RF/Cryo Catheter Ablation.
At the 2026 AF Symposium, Dr. Vivek Reddy (Mount Sinai Medical Center, New York, NY) gave a presentation on “Long Term Outcomes of Pulsed Field Ablation (PFA) versus Standard of Care Thermal Ablation for Paroxysmal Atrial Fibrillation: Primary Results of the ADVENT-LTO Study.
The ADVENT-LTO was a follow-up study to the original The ADVENT study. This nearly 4-year study followed PFA and thermal ablation patients, basically an observational extension of the original ADVENT trial.
PFA Versus Thermal Ablation
Researchers used Holter monitors, patients’ clinical records, and quality of life surveys to conduct the study.
The primary end point was freedom from recurrence beyond the 3-month blanking period, cardioversions, or repeat ablations.
The PFA group included 183 patients, the thermal ablation group included 181 (81 RF ablation patients and 100 Cryo ablation patients)…Continue reading to learn the study findings and what it means to Atrial Fibrillation patients->
The exhibition hall at the AF Symposium with manufacturers specializing in ablation catheters, LAA closure devices, and mapping systems, as featured in the sessions.
