Is There a Pulsed Field Ablation in Your Future? Groundbreaking Innovation in Atrial Fibrillation!
One of the most important, groundbreaking innovations in Atrial Fibrillation (A-Fib) treatment is Pulsed Field Ablation. PFA is widely approved and used in Europe beginning in 2021.
In the U.S., the FDA approved the first Pulsed Field Ablation system in January 2024. There are now five FDA-approved Pulsed Field Ablation systems: Boston Scientific’s Farapulse, Medtronic’s Affera, Medtronic’s Pulse Select, Johnson & Johnson’s Varipulse, and Abbott’s Volt.
What Makes Pulsed Field Ablation Different
Preceding Pulsed Field Ablation, the two main energy systems for catheter ablation were thermal, i.e., radiofrequency (RF) (heat) and Cryo (freezing).
Pulsed Field Ablation instead uses a fundamentally different process called “Irreversible Electroporation”.
Illustration of damaged esophagus during catheter ablation: Left, RF ablation; Center, CryoBalloon ablation; Right, Normal Esophagus with Pulsed Field Ablation.During Irreversible Electroporation, an instantaneous electrical field is applied to targeted cells which open up tiny doors (nanopores). Shortly thereafter, the contents of the cell exit through these doors, and the cell dies. The cell is rendered electrically inactive.
Unlike ablated tissue using RF and Cryo thermal energy, PFA retains the cell’s original structure even after cell death. Because it doesn’t rely on thermal effects, there is no charring or crust formation. ->Continue reading about Pulsed Field Ablation->





