Study of Dementia Risk: Catheter Ablation for A-Fib Versus Drug Therapy Alone
Historically, dementia in patients with A-Fib was attributed to strokes.
Recently it has become clear that A-Fib is associated with multiple forms of dementia even in the absence of stroke.
As anyone with an aging loved one suffering from dementia can tell you, dementia is a major health problem. In the U.S., dementia is predicted to affect more than 10.5 million Americans by 2050.
Research: Risks of Ablation vs. Drug Therapy
In an observational study, researchers compared A-Fib patients who had a catheter ablation to those treated with drug therapy alone.
They used the 2010 to 2021 data from a large, nationally representative claims database (Optum Clinformatics Data) to identify 19,088 A-Fib patients. They then divided these patients into two groups: those receiving a catheter ablation vs those receiving anti-arrhythmic drug (AAD) therapy alone.
Findings: Risks of Dementia and Mortality
Dementia Risk: They found that catheter ablation for A-Fib was associated with a 41% lower risk of dementia compared to patients treated only with anti-arrhythmic drug therapy. This dementia risk reduction held across both males and females.
Mortality Risk: Though not studied as a primary outcome, researchers found patients treated with catheter ablation also had a 49% lower rick of mortality compared with anti-arrhythmic drug therapy only.
What This Means to Patients
Catheter Ablation, by reducing the risk of dementia by 41%, is a major advance in our knowledge about health care for A-Fib patients.
This is yet another reason to get a catheter ablation ASAP in order to be A-Fib free.