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The CHADS2 & CHA2DS-VASc Stroke-Risk Grading Systems

Stroke-Risk Grading Systems

Stroke-Risk Grading Systems

By Steve S. Ryan, PhD, Updated Nov 2014

In the US, doctors use what is called a CHADS2 stroke-risk grading system to help estimate the risk of stroke in patients with atrial fibrillation. A high CHADS2 score corresponds to a greater risk of stroke, while a low CHADS2 score corresponds to a lower risk of stroke. The CHADS2 score is simple and has been validated by many studies.

The patient’s stroke risk, i.e., their CHADS2 score, is estimated by adding together the points that correspond to the patient’s conditions.

“C” Congestive Heart Failure Score = 1

“H” Hypertension Score = 1

“A” Age over 75 Score = 1

“D” Diabetes Score = 1

“S2” Previous Stroke or TIA Score = 2

 A CHADS2 score of 2 or over would indicate someone should be on a blood thinner such as warfarin.

The CHADS2 score has been superseded in clinical use by the CHA2DS2-VASc score that is designed to give a better stratification of low-risk patients. It utilizes the same 5 major risk factors considered by CHADS2 but assigns a score of ‘2’ for patients older than 75 years, and adds 3 new risk factors: a history of vascular disease, age 65-74 years, and female sex which increase stroke risk. But according to the original study, “there was no statistically significant difference found between the CHA2DS2-VASc and CHADS2 risk stratification schema in predicting TE events”.

A-Fib Stroke Risk Calculators

CHAD2DS2VAC Medium 100 pix at 96 resUse this link to calculate your A-Fib stroke risk using the CHADS2 Calculator
Use this link to calculate your A-Fib stroke risk using the CHA2DS2-VASc Calculator

Classification of CHADS2 vs CHA2DS-VASc

In both scoring systems, a score of 0 is “low” risk of stroke, 1 is “moderate”, and any score above 1 is a “high” risk. The CHA2DS2-VASc system has three more variables and therefore will classify a greater number of patients into a high-risk group.

Editor’s comment: There is some controversy about the increased stroke risk for females. See articles on Dr. John M’s blog post and Aging Well magazine.
See also our article: Women in A-Fib Not at Greater Risk of Stroke, and The New CHA2DS2-VASc Guidelines and the Risks of Life-Long Anticoagulation Therapy.

References for this article

Hwang, Calvin. CHA2DS2-VASc Score for Atrial Fibrillation Stroke Risk. http://www.mdcalc.com/cha2ds2-vasc-score-for-atrial-fibrillation-stroke-risk/ Last accessed 6/15/15.

Lip, GYH et al. Refining Clinical Risk Stratification for Predicting Stroke and Thromboembolism in Atrial Fibrillation Using a Novel Risk Factor-Based Approach: The Euro Heart Survey on Atrial Fibrillation. Thromboembolism. February 2010. http://www.ncbi.nlm.nih.gov/pubmed/19762550. Last accessed 6/15/15.

Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ (2001). Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA 285 (22): 2864–70. doi:10.1001/jama.285.22.2864. PMID 11401607. http://jama.ama-assn.org/cgi/content/full/285/22/2864.

Gage BF, van Walraven C, Pearce L, et al. (2004). Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin. Circulation 110 (16): 2287–92. doi:10.1161/01.CIR.0000145172.55640.93. PMID 15477396. http://circ.ahajournals.org/cgi/content/full/110/16/2287.

Atrial Fibrillation is a Major Risk Factor for Stroke. Thrombosis Adviser website. Last accessed November 15, 2014. URL: http://www.thrombosisadviser.com/en/atrial-fibrillation/af-is-a-major-stroke-risk-factor/

Mandrola J. Female gender and stroke risk in atrial fibrillation: Know your CHA2DS2-VASc Score. Last accessed Jan 10, 2013 URL: http://www.drjohnm.org/atrial-fib/female-gender-and-stroke-risk-in-atrial-fibrillation-know-your-cha2ds2-vasc-score/

Older Women With Atrial Fibrillation at 20% Greater Risk of Stroke, Aging Well. Last accessed Jan 10, 2013 URL: http://www.agingwellmag.com/news/090412_news.shtml

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Last updated: Thursday, September 3, 2015

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